International Conference​

Exploring the Future of Inhalation Drug Delivery

SECOND EDITION

Parma, Italy

• Conference: 8-10th September
• Pitch Contest: 11th September

 

 

 

AGENDA

Activity Time
Registration
Poster installation
Exhibitors’ setup
09:00 – 14:00

 

SPEAKER TITLE TIME
Prof. Paolo Martelli
(University Rector)
Francesca Buttini
(University of Parma)
Conference opening: Welcome and Introduction       14:00-14:20

 

 

NEW PARADIGMS IN LUNG DELIVERY

 

Chairs: Ruggero Bettini and Joanne Peart

Keynote Speaker:

Melanie Ott
(Gladstone Institutes)

In the Air Around Us: Understanding and Outpacing Viral Threats 14:20 – 15:00
Fabien Barbirato
(Sanofi)
IBeyond the Needle: Engineering Novel mRNA Lipid Nanoparticle Formulations for Respiratory Mucosal Vaccination 15:00 – 15:25
Philip Kwok
(University of Sidney)
Probiotic-bacteriophage aerosols for treating bacterial lung
infections
15:25 – 15:50

COFFEE BREAK + POSTER SESSION

Chairs: Julie Suman and Francesca Buttini

Andrea Casazza
(Chiesi Farmaceutici)
Disease‑First, a Strategy for Next‑Generation Inhaled Medicines 16:30 – 16:55
Michael Goller
(TranspireBio)
Expanding Inhalation Therapies beyond Asthma and COPD 16:55 – 17:20
Lucas Silva
(Aptar Pharma)
Breaking Barriers in Biologics Delivery: Advanced Nasal and Pulmonary Delivery of Large Proteins and Nucleic Acids 17:20 – 17:30
Anselm Ebert
(H&T Presspart)
Navigating Inhalation Trends: Delivering Innovative, Sustainable Device Solutions 17:30 – 17:40

WELCOME RECEPTION (17:40 – 19:00)

 

 

AEROSOLS OF LUNG INFECTION

 

Chairs: Irene Rossi

Sara Maloney
(RTI International)
Formulation Strategies for Inhaled NTM Therapies 09:00 – 09:25
Mercedes Gonzalez-Huarrero
(Colorado State University)
Preclinical development of aerosol therapy for M. abscessus pulmonary disease 09:25 – 09:50
Rahul Kumar Verma
(Institute of Nano Science and
Technology Mohali)
Inhalable self-propelled Autonomous micro motors for
Tuberculosis therapeutics
09:50 – 10:05
Miles Kottman
(Bespak)
Beyond the propellant: taking the next step in low carbon pMDIs 10:05 – 10:15

COFFEE BREAK + POSTER SESSION

 

PRESSURISED METERED DOSE INHALES AT 70

 

Chairs: Daniela Traini and Geraldine Venthoye

John Pritchard
(Inspiring Strategies)
Is the transition to lower global-warming propellants on schedule? 11:00 – 11:20
Sheryl Johnson
(Orbia)
pMDI Formulation at 70: Unlocking HFA 152a for the Next Generation 11:20 – 11:30
Mark Boelens
(Solstice)
Evolving Regulatory Landscape for the Adoption of Low
Global Warming Potential (LGWP) Propellants
11:30 – 11:40
Paul Young – David Lewis
(Oz-Uk Ltd)
From First Principles to Representative Performance: pMDIs in the Low-GWP Era 11:40 – 12:00
Stephen Stein
(CGT Pharma Consulting)
Developing Suitable Suspension MDI Formulations in LGWP Propellants 12:00 – 12:20
ROUND TABLE

pMDIs at 70: What does the future hold?

John Pritchard – Nick Smalley (Kindeva) – Stephen Stein – Paul Young

12:20 – 13:00

LIGHT LUNCH + POSTER SESSION

 

MUCUS-PENETRATING PARTICLES AND RNA DELIVERY

 

Chairs: Alessandro Fioni and Ben Forbes

Keynote Speaker
Justin Hanes
(Johns Hopkins University)
The Airway Mucus Barrier and How to Overcome it   14:15 – 14:55
Rémi Rosière
(InhaTarget Therapeutics)
Lung Delivery of Nucleic Acid–Loaded Lipid Nanoparticles to Tackle High Unmet Needs in Respiratory Medicine 14:55 – 15:20
Koen Raemdonck
(Ghent University)
Inhalable RNA formulations for pulmonary diseases 15:20 – 15:45
Franziska Dahlmann
(Fraunhofer ITEM, Hannover)
Translational development of an inhaled palmitoyl-conjugated antiviral siRNA against Human
Parainfluenza virus infection
15:45 – 16:00

COFFEE BREAK + POSTER SESSION

ROUND TABLE 1000 Years of Experience, 16 Years of Progress: What Still Remains?
Chair: Jayne Hastedt

Per Bäckman (Emmace AB) – Andy Clark (InStatin Inc., remote) – Paolo Colombo (PlumeStars) – Carsten Ehrhardt (Trinity College Dublin) – Ben Forbes (King’s College London) – Anthony Hickey (RTI International) – John Patton (Kindeva) – Jeffrey Weers (PhIAT, remote) 

16:30 – 17:30

 

NEW PERSPECTIVES ON AIRWAY INFLAMMATION AND CHRONIC COUGH

 

Chairs: Stefano Aliberti and Gaetano Caramori

Keynote Speaker
David Edwards
(SC Therapeutics)
Airway inflammation and hypertension 09:00 – 09:40
Federico Lavorini
(Careggi University Hospital)
Clinical Aspects and Pathophysiology of Chronic Cough 09:40 – 10:05
Alyn Morice
(University of Hull)
Chronic Cough Management: From Current Treatments to Emerging Therapies 10:05 – 10:30
Diletta Mandrioli
(University of Parma)
Carcainium Dry Powder Inhaler for Prolonged Chronic Cough Treatment 10:30 – 10:45

COFFEE BREAK + POSTER SESSION

Stefano Aliberti
(Humanitas Research Hospital)
Non–cystic fibrosis bronchiectasis and emerging therapeutic strategies 11:30 – 11:55
Valentina Fainardi
(Parma University Hospital)
Comparative Profiling of the Airway and Gut Microbiota in Cystic Fibrosis and Primary Ciliary Dyskinesia 11.55 – 12:15
Philip Kuehl
(Aptar Pharma)
Preclinical Tools for Advancing Pulmonary and Nasal Drug Products 12:15 – 12:35
Murat Ali
(Phillips Medisize)
Enabling Therapies Today and Tomorrow: Demonstrating the Versatility of Blister-Based Dry Powder Inhalers for Current and Future Drug Delivery 12:35 – 13:00

LIGHT LUNCH + POSTER SESSION

NASAL DELIVERY OF BIOLOGICS AND RNA

Chairs: Regina Scherliess & Fabio Sonvico

Nathalie Heuzé-Vourc’h
(National Institute of Biomedical
Research)
Exploring Intranasal Delivery of Anti-Infective Antibodies 14:30 – 14:55
Chantelle Ahlenstiel
(Kirby Institute)
Respiratory delivery of antiviral RNA therapeutics 14:55 – 15:20
Katharina Schindowski
(Biberach University)
Intranasal nose-to-brain delivery of a monoclonal antibody with a controlled release drug delivery system: proof-ofconcept and pharmacokinetic studies in mini pigs 15:20 – 15:45

COFFEE BREAK + POSTER SESSION

Chairs: Teresa M. Carvajal and Daniela Traini

Brianna Walz
(University of Toronto)
Optimization and Mechanistic Characterization of Intranasal mRNA-Lipid Nanoparticles for Systemic Protein Secretion 16:15 – 16:30
Ana Fortuna
(University of Coimbra)
From First Principles to Measured Performance: pMDIs in the Low-GWP Era 16:30 – 16:50
Francesca Buttini
(University of Parma)
CLOSING REMARKS 16:45 – 17:00

GALA DINNER

CONFIRMED PLENARY SPEAKERS

David  Edwards
SC Therapeutics, US

Justin Hanes
Johns Hopkins University, US

CONFIRMED INVITED SPEAKERS

Michael Goller
Transpire Bio, US

Philip Kuehl
Aptar Pharma, US

Philip Kwok
University of Sydney, Australia

David Lewis
Oz-UK Ltd, UK

Sara Maloney
RTI International, US

Alyn Morice
University of Hull, UK

John Pritchard
Inspiring Strategies, UK

 

Koen Raemdonck
Ghent University, Belgium

Rémi Rosière
InhaTarget Therapeutics, Belgium

Katharina Schindowski
Biberach University, Germany

Steve Stein
CGT Pharma Consulting, US

Nathalie Heuzé-Vourc’h
National Institute of Biomedical Research, France

SPEAKERS FROM OUR PLATINUM SPONSORS

Anselm Ebert
H&T Presspart

Mark Boelens
Solstice

Miles Kottman
Bespak

Lucas Silva
Aptar Company